Natural movement behaviour exhibits complexity and variability that surpasses what is observed in laboratory-based settings. Measuring natural movement behaviour is crucial because it accurately represents an individual’s functional status and disability in real-life contexts. This enhanced understanding is vital for assessing the impact of interventions, particularly in individuals with neurological diseases, where specific movements like reaching, drinking, and walking are critical indicators of motor learning and recovery. Accurate measurement of these behaviours supports the development of tailored rehabilitation strategies, ultimately leading to improved treatment outcomes. Striving to bridge the gap between advanced technology and practical clinical application, our research lab focuses on developing valid detection of physical activities and implementing sensor-based monitoring and meaningful outcomes in rehabilitation clinics.