We study how the injured brain recovers—and how that knowledge can be turned into better, more personalized therapy.
Our work spans two complementary aims. First, we investigate the neurophysiological mechanisms of recovery after stroke and other neurological injuries: how neural networks reorganize, which biological and behavioral factors shape recovery trajectories, and why patients respond differently to treatment. Second, we use these insights to develop targeted rehabilitation interventions, with a particular focus on high-dose, high-intensity, and technology-enhanced approaches that extend beyond the traditional therapy setting.
Methodologically, we combine neuroimaging, non-invasive brain stimulation, behavioral assessment, digital tools, and clinical outcome measures. This enables us to connect changes at the level of the nervous system with meaningful functional recovery, and to identify new therapeutic targets for neurorehabilitation.
A growing part of our portfolio focuses on making intensive rehabilitation feasible, adaptive, and sustainable in real-world care. Through initiatives such as SwissNeuroRehab, ISRRA, and HDHI-related programs, we develop home-based and digitally supported interventions that can deliver higher therapy doses while remaining engaging for patients, actionable for therapists, and implementable within healthcare systems.
Our long-term vision is a neurorehabilitation model that integrates biological mechanism, patient behavior, therapist expertise, and system-level implementation. In doing so, we aim to move the field beyond one-size-fits-all protocols toward personalized, evidence-informed recovery pathways.
Research Axes
LLUI currently has three more core axes of research. Find an overview of all research groups and their individual research by clicking below
Group Lead